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FP7 Partner offer profile

Voronezh State University - KBBE-2009-1-3-03: Bee health: identification of emerging honey bee pest and diseases and reemergence of pathogens and explaining the intimate mechanisms and the reasons for increased honey bee mortality

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Date of filling in 23.09.2008
Organization name Voronezh State University
Organization adress Universitetskaya pl., 1, Voronezh, 304006, Russia
Department/Unit Chair of Genetics, Cytology and Bioengenering
Contact person DSc, Prof. Vasily N. Popov, Head of Chair
Phone +7-4732-208875
Fax +7-4732-208755
E-Mail pvn@bio.vsu.ru
Web-site http://www.vsu.ru
Organization type
  • Research
  • Education
Special Programme
Theme
Food, Agriculture and Fisheries, and Biotechnology (KBBE)
Call identifier
FP7-KBBE-2009-3
Topic number KBBE-2009-1-3-03: Bee health: identification of emerging honey bee pest and diseases and reemergence of pathogens and explaining the intimate mechanisms and the reasons for increased honey bee mortality
Call Deadline 15.01.2009
Short description of the organization (max 12 lines): Voronezh State University (VSU) was established in 1918 on the base of evacuated from Estonia Russian Derpt University (est. 1802). VSU (23,000 of students/2500 staff/460 full professors) is in top 10 of Russian universities. The university consists of 18 schools including 2 schools of economics, schools of biology, chemistry, geoecology, which could be involved in project. Natural research in these subjects is cariedout by Natural reserve “Galichya Gora”, Biological station and Botanical Garden? Included to university structure.
Expertise offered The penetration of modern European technologies into the Russian agriculture has resulted in growing recognition of the economical importance of bees and bumblebees in pollinating the mainstream crops. However, their usage is still very limited in conditions of greenhouse due to the sub-optimal performance and short longevity of the imported bee and bumblebee colonies and their relatively high price. However, the former problem is likely rooted in the agricultural practices used in Russian greenhouses. The first our proposal for this project is to elucidate the causes for the sub-optimal performance and short economical lifespan of artificially reared bee and bumblebee colonies in the conditions of greenhouses. Specifically, we hypothesize that commonly used domestic pesticides impair the flight performance and decrease the longevity of bumblebees by damaging their mitochondrial metabolism. The first Aim of this proposal is to investigate the impact of the c pesticides on the flight muscle mitochondria and the flight performance and longevity of bees and bumblebees. The second objective of our proposal addresses a unique biochemical problem associated with the extremely high rate of oxygen consumption in the flight muscle of bumblebees. We hypothesize that it should result in the high rate of the production of mitochondrial reactive oxygen species (ROS) and oxidative damage to the flight muscle tissue, unless it possesses a powerful ROS-detoxifying mechanism. The second Aim of this proposal is to elucidate both the mechanism of ROS production and removal in the mitochondria of different bee species flight muscle. We will examine the rate of ROS production the activity of the mitochondrial antioxidant enzymes, the role of ROS removal by gaseous diffusion, and the antioxidant properties of flight muscle extracts. We anticipate that completing this project may yield significant economic benefits and further boost the use of bumblebees in agriculture and greenhouse industry. We also anticipate that elucidating the ROS metabolism in bumblebee’s mitochondria may benefit both the basic and biomedical science by contributing to the development of an efficient therapeutic approach to combat the oxidative stress involved in etiology of a great number of human pathologies.
Scientific keywords -
Publications on the topic (other references)
  • Popov V.N. , Volvenkin S.V., Eprintcev A.T., Igamberdiev A.U. Presence of Glyoxylate Cycle Enzymes in Liver of Alloxan-Treated Rats // FEBS Letters 1998, V.440. P. 55-58.
  • Popov V.N., Igamberdiev A.U., Schnarrenberger C., Volvenkin S.V. (1996) Induction of the Glyoxylate Cycle Enzymes in Rat Liver upon Food Starvation.- FEBS Letters 390, 287-290.
  • Popov V.N., Simonyan R.A., Skulachev V.P., Starkov A.A. Inhybition of alternative oxydase induses H2O2 production in plant mitochondria // FEBS Letters, 1997 V. 415, N1, P. 87-90.
  • Popov V.N., Purvis A.C., Skulachev V.P, Wagner A.M. Stress-induced changes in ubiquinone concentration and alternative oxidase in plant mitochondria // Bioscience Reports. 2001. V. 21, N 3. P. 369-379.
  • Popov V., Markova O., Mokhova E., Skulachev V.P. Effects of in vivo cold exposure and in vitro uncouplers and recouplers on potato tuber mitochondria // Biochem. Biophys. Acta. 2002 V. 1553, P. 232-237.
  • Popov V.N. Possible role of free oxidation processes in regulation of reactive oxygen species production in plant mitochondria (review) // Biochem. Soc. Transactions. 2003. V. 31, N. 6, P. 1316-1317.
  • Popov V.N., Ruuge E.K., Starkov A.A. Electron transport inhybitors influence on reactive oxygen species production in pea mitochondria // Biochemistry (Moscow), 2003. Т. 68, N 7. P. 910-916.
  • Lopatin A.V. The sequence of substrate wall cells construction in гнездах Seladonia subaurata (Rossi), (Hymenoptera, Halictidae) // Russian Zoological J.. 2003. V. 82, № 12. P. 1462-1465.
  • Lopatin A.V.. Trgub T.F. The study of traffic connection of Seladonia subaurata (Rossi) (Hymenoptera, Halictidae) bee using germ from nests cells // Russian J. of Ecology. 2004, V.4. С. 297-300
  • Eprintsev A.T., Shevchenko M.Yu., Popov V.N. Purification and properties of isocitrate lyase from pupae of Papilio machaon butterfly// Biochemistry (Moscow). 2004. V.69, N 4, P. 376-380.
Description of previous and present experience in International Cooperation -
Previous participation in EU’s Framework Programme projects